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kw.\*:("Fosmidomicina")

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The methylerythritol phosphate pathway for isoprenoid biosynthesis in coccidia : Presence and sensitivity to fosmidomycinCLASTRE, Marc; GOUBARD, Armelle; PREL, Anne et al.Experimental parasitology. 2007, Vol 116, Num 4, pp 375-384, issn 0014-4894, 10 p.Article

Bioassay for determination of fosmidomycin in plasma and urine : Application for pharmacokinetic dose optimisationCHEOYMANG, Anurak; HUDCHINTON, David; KIOY, Deborah et al.Journal of microbiological methods. 2007, Vol 69, Num 1, pp 65-69, issn 0167-7012, 5 p.Article

Assessment of in vitro antimalarial interactions between dihydroartemisinin and fosmidomycinCHAIJAROENKUL, Wanna; PRUKTAL, Pattaya; MUHAMAD, Poonuch et al.Southeast Asian journal of tropical medicine and public health. 2007, Vol 38, Num 5, pp 791-795, issn 0125-1562, 5 p.Article

1-deoxy-D-xylulose 5-phosphate reductoisomerase (IspC) from Mycobacterium tuberculosis : Towards understanding mycobacterial resistance to fosmidomycinDHIMAN, Rakesh K; SCHAEFFER, Merrill L; BAILEY, Ann Marie et al.Journal of bacteriology. 2005, Vol 187, Num 24, pp 8395-8402, issn 0021-9193, 8 p.Article

Fosmidomycin-clindamycin for Plasmodium falciparum infections in African childrenBORRMANN, Steffen; ADEGNIKA, Ayola A; MATSIEGUI, Pierre-Blaise et al.The Journal of infectious diseases. 2004, Vol 189, Num 5, pp 901-908, issn 0022-1899, 8 p.Article

Synthesis of β-and γ-oxa isosteres of fosmidomycin and FR900098 as antimalarial candidatesHAEMERS, Timothy; WIESNER, Jochen; GIESSMANN, Dirk et al.Bioorganic & medicinal chemistry. 2008, Vol 16, Num 6, pp 3361-3371, issn 0968-0896, 11 p.Article

Synthesis and antimalarial activity of chain substituted pivaloyloxymethyl ester analogues of Fosmidomycin and FR900098KURZ, Thomas; SCHLÜTER, Katrin; KAULA, Uwe et al.Bioorganic & medicinal chemistry. 2006, Vol 14, Num 15, pp 5121-5135, issn 0968-0896, 15 p.Article

Fosmidomycin resistance in adenylate cyclase deficient (cya) mutants of Escherichia coliSAKAMOTO, Yoshiko; FURUKAWA, Soichi; OGIHARA, Hirokazu et al.Bioscience, biotechnology, and biochemistry. 2003, Vol 67, Num 9, pp 2030-2033, issn 0916-8451, 4 p.Article

Isoprene increases thermotolerance of fosmidomycin-fed leavesSHARKEY, Thomas D; XIUYIN CHEN; SANSUN YEH et al.Plant physiology (Bethesda). 2001, Vol 125, Num 4, pp 2001-2006, issn 0032-0889Article

Modifications around the hydroxamic acid chelating group of fosmidomycin, an inhibitor of the metalloenzyme 1-deoxyxylulose 5-phosphate reductoisomerase (DXR)ZINGLE, Catherine; KUNTZ, Lionel; TRITSCH, Denis et al.Bioorganic & medicinal chemistry letters (Print). 2012, Vol 22, Num 21, pp 6563-6567, issn 0960-894X, 5 p.Article

The Apicoplast: A Key Target to Cure MalariaMACRAE, James I; MARECHAL, Eric; BIOT, Christophe et al.Current pharmaceutical design (Print). 2012, Vol 18, Num 24, pp 3490-3504, issn 1381-6128, 15 p.Article

Evaluation of fosmidomycin analogs as inhibitors of the Synechocystis sp. PCC6803 1-deoxy-D-xylulose 5-phosphate reductoisomeraseWOO, Youn-Hi; FERNANDES, Roberta P. M; PROTEAU, Philip J et al.Bioorganic & medicinal chemistry. 2006, Vol 14, Num 7, pp 2375-2385, issn 0968-0896, 11 p.Article

Fosmidomycin for malariaMISSINOU, Michel A; BORRMANN, Steffen; JOMAA, Hassan et al.Lancet (British edition). 2002, Vol 360, Num 9349, pp 1941-1942, issn 0140-6736, 2 p.Article

Molecular epidemiology of malaria in cameroon. XXV. In Vitro activity of fosmidomycin and its derivatives against fresh clinical isolates of Plasmodium falciparum and sequence analysis of 1-deoxy-D-xylulose 5-phosphate reductoisomeraseTAHAR, Rachida; BASCO, Leonardo K.The American journal of tropical medicine and hygiene. 2007, Vol 77, Num 2, pp 214-220, issn 0002-9637, 7 p.Article

Randomized controlled trial of fosmidomycin-clindamycin versus sulfadoxine -pyrimethamine in the treatment of Plasmodium falciparum malariaOYAKHIROME, Sunny; ISSIFOU, Saadou; PONGRATZ, Peter et al.Antimicrobial agents and chemotherapy. 2007, Vol 51, Num 5, pp 1869-1871, issn 0066-4804, 3 p.Article

Fosmidomycin plus clindamycin for treatment of pediatric patients aged 1 to 14 years with Plasmodium falciparum malariaBORRMANN, Steffen; LUNDGREN, Ingrid; JOMAA, Hassan et al.Antimicrobial agents and chemotherapy. 2006, Vol 50, Num 8, pp 2713-2718, issn 0066-4804, 6 p.Article

Determination of fosmidomycin in human serum and urine by capillary electrophoresisBRONNER, Stéphane; RENAULT, Corinne; HINTZ, Martin et al.Journal of chromatography. B. 2004, Vol 806, Num 2, pp 255-261, issn 1570-0232, 7 p.Article

The MEP pathway: A new target for the development of herbicides, antibiotics and antimalarial drugsRODRIGUEZ-CONCEPCION, M.Current pharmaceutical design. 2004, Vol 10, Num 19, pp 2391-2400, issn 1381-6128, 10 p.Article

Fosmidomycin, a novel chemotherapeutic agent for malariaLELL, Bertrand; RUANGWEERAYUT, Ronnatrai; WIESNER, Jochen et al.Antimicrobial agents and chemotherapy. 2003, Vol 47, Num 2, pp 735-738, issn 0066-4804, 4 p.Article

Synthesis and evaluation of phosphonated N-heteroarylcarboxamides as DOXP-reductoisomerase (DXR) inhibitorsBODILL, Taryn; CONIBEAR, Anne C; BLATCH, Gregory L et al.Bioorganic & medicinal chemistry. 2011, Vol 19, Num 3, pp 1321-1327, issn 0968-0896, 7 p.Article

The Methylerythritol Phosphate (MEP) Pathway for Isoprenoid Biosynthesis as a Target for the Development of New Drugs Against Tuberculosis : Protein targets for development of drugs against Mycobacterium tuberculosisOBIOL-PARDO, C; RUBIO-MARTINEZ, J; IMPERIAL, S et al.Current medicinal chemistry. 2011, Vol 18, Num 9, pp 1325-1338, issn 0929-8673, 14 p.Article

Antibacterial and antitubercular activity of fosmidomycin, FR900098, and their lipophilic analogsUH, Eugene; JACKSON, Emily R; JOSE, Géraldine San et al.Bioorganic & medicinal chemistry letters (Print). 2011, Vol 21, Num 23, pp 6973-6976, issn 0960-894X, 4 p.Article

Substitution of the phosphonic acid and hydroxamic acid functionalities of the DXR inhibitor FR900098: An attempt to improve the activity against Mycobacterium tuberculosisANDALOUSSI, Mounir; LINDH, Martin; BJÖRKELID, Christofer et al.Bioorganic & medicinal chemistry letters (Print). 2011, Vol 21, Num 18, pp 5403-5407, issn 0960-894X, 5 p.Article

Divergent strategy for the synthesis of α-aryl-substituted fosmidomycin analoguesDEVREUX, Vincent; WIESNER, Jochen; JOMAA, Hassan et al.Journal of organic chemistry. 2007, Vol 72, Num 10, pp 3783-3789, issn 0022-3263, 7 p.Article

Targeting the methyl erythritol phosphate (MEP) pathway for novel antimalarial, antibacterial and herbicidal drug discovery : Inhibition of 1 -deoxy -D-xylulose -5 -phosphate reductoisomerase (DXR) enzymeSINGH, Nidhi; CHEVE, Gweneal; AVERY, Mitchell A et al.Current pharmaceutical design. 2007, Vol 13, Num 11, pp 1161-1177, issn 1381-6128, 17 p.Article

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